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2022 PRIM&R Annual Conference

Emerging Challenges and Breaking Issues

Shared Oversight Challenges

PRIM&R Service Award Presentation, and Plenary III: Lost in Translation

Tuesday, December 13, 2022
10:00 AM – 11:30 AM ET
Location: Livestreamed
Livestreaming Session Icon Crossover Thought Leader Series
PRIMR22 day two will start with the presentation of the PRIM&R Service Award to Clement A. Adebamowo, BM, ChB, ScD, FWACS, FACS, Professor, University of Maryland School of Medicine, followed by Plenary III.

Plenary III Descriptor:Why do most drugs and other basic science findings fail to translate into human outcomes? Can changes in animal research help resolve this problem? This session will explore animal models and translatability to human diseases and conditions through the lens of study design, physiology, toxicity studies, reverse translation, and reproducibility. Session attendees will explore how animal and human subject researchers and oversight committees can learn about what doesn’t work, how past failures have led to successes, and how to work together to produce better research outcomes.

Learning Objectives:

  • Discuss the failure of translatability in current animal to human research, and when failures led to successes
  • Identify the issues in research design that lead to poor translatability
  • Explore mitigation strategies to improve future animal to human research