D02 - Equitable Inclusion and Local Community Context in Multi-Site Research

Multi-site trials offer the opportunity to include adequate numbers of subjects from a range of populations, and findings with greater relevance to more people. While the 2018 requirements for single IRBs position the single IRB to have a comprehensive perspective on the overall population recruited for the trial, the membership may not be knowledgeable about the issues most relevant to each participant community. This session will address strategies for facilitating community competence of the single IRB and consider when the distinctive features of a community may indicate the need for additional review or an exception to single IRB review.